CALL FOR PAPERS Physiological Genomics of Exercise in Health and Disease Multi-omic integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in Type 2 diabetic obesity
نویسندگان
چکیده
David S. Rowlands, Rachel A. Page, William R. Sukala, Mamta Giri, Svetlana D. Ghimbovschi, Irum Hayat, Birinder S. Cheema, Isabelle Lys, Murray Leikis, Phillip W. Sheard, St. John Wakefield, Bernhard Breier, Yetrib Hathout, Kristy Brown, Ramya Marathi, Funda E. Orkunoglu-Suer, Joseph M. Devaney, Benjamin Leiken, Gina Many, Jeremy Krebs, Will G. Hopkins, and Eric P. Hoffman School of Sport and Exercise, Massey University, Wellington, New Zealand; Institute of Food, Nutrition & Human Health, Massey University, New Zealand; Children’s National Medical Center, Center for Genetic Medicine Research (CGMR), Washington, District of Columbia; School of Science and Health, University of Western Sydney, Campbelltown, Australia; Faculty of Engineering, Health, Science and the Environment, Charles Darwin University, Australia; Wellington Hospital, Capital and Coast District Health Board, Wellington, New Zealand; Endocrine and Diabetes Unit, Capital and Coast District Health Board, Wellington, New Zealand; Department of Physiology, University of Otago, Dunedin, New Zealand; Department of Pathology, University of Otago, Wellington, New Zealand; and Health Science/Sport and Recreation, Auckland University of Technology, Auckland, New Zealand
منابع مشابه
Multi-omic integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in Type 2 diabetic obesity.
Epigenomic regulation of the transcriptome by DNA methylation and posttranscriptional gene silencing by miRNAs are potential environmental modulators of skeletal muscle plasticity to chronic exercise in healthy and diseased populations. We utilized transcriptome networks to connect exercise-induced differential methylation and miRNA with functional skeletal muscle plasticity. Biopsies of the va...
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Background & Aims: Performing normal daily activities requires sufficient muscle size and strength, and atrophy has a negative effect on the overall quality of life; So that the decrease in skeletal muscle mass leads to a decrease in human performance, long-term health and low quality of life. Diabetes is associated with the development of secondary complications in various organs, especially s...
متن کاملTHE EFFECTS OF INTERVAL TRAINING INTENSITY ON SKELETAL MUSCLE PGC-1Α IN TYPE2 DIABETIC MALE RATS
Background: The purpose of this study was to compare the effects of a 12 weeks interval training with high and moderate intensity on PGC-1α of skeletal muscle in type 2 diabetic male rats. Methods: 40 male rats were divided into two groups: High fat diet (HFD) (n=32) and standard diet (C) (n=8) for 10 weeks. After inducing type2 diabetes via STZ, 8 diabetic rats (D) and 8 rats in group C rats ...
متن کاملEffect of Resistance Exercise and Training and Principles of Prescribing it for Cardiovascular Patients
Introduction: The importance and necessity of preventing the occurrence of these diseases in order to maintain and promote health, has attracted the attention of many researchers to methods of preventing the occurrence of cardiovascular injury. Metabolic effects of muscle mass loss due to the natural aging process are caused by decreased muscle activity and lead to high prevalence of obesity, i...
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تاریخ انتشار 2014